A 32-year-old female presents with intermittent diplopia. She describes no other symptoms. She has no past medical history. Your abnormal examination findings of the patient are as below.

Intermittent diplopia

1. State the clinical finding. 1 mark

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2. What anatomical structure is involved? 1 mark

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You suspect first presentation multiple sclerosis.

3. What is Uthoff’s phenomenon? 1 mark

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4. What other brainstem neuropathology would you consider and examine for that has associations with MS? 3 marks

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5. Fill the table differentiation MS from Acute Disseminated Encephalomyelitis. 6 marks

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