A 78-year-old woman presents to ED with acute onset dysphasia and right upper limb weakness. CT imaging is consistent with an ischaemic stroke. Thrombolysis is being considered for this patient.

1. Give (6) absolute contraindications to thrombolysis (not including lab investigation parameters). 6 marks

During thrombolysis, the patient becomes increasingly hypertensive.

2. Prescribe first and second-line antihypertensive therapy and give your target BP. 3 marks

3. Other than the development of a focal neurological deficit or worsening hypertension, what clinical features may indicate that thrombolysis has been complicated by an intracerebral haemorrhage? 4 marks

4. Outline the emergency management principles of post-thrombolysis intracerebral haemorrhage. 5 marks