A 10-year-old boy with known Haemophilia A presents to the emergency department with an atraumatic painful knee. He is systemically well. His X-ray shows no fracture. His weight is 30kg and his vitals are normal.

1. What is Haemophilia A? 1 mark

2. Complete the table with the concentration of clotting factors for each level of severity. 3 marks

3. What is the likely diagnosis? 1 mark

4. List (2) supportive management steps. 2 marks

5. State the specific management, including dose and targets. 3 marks

6. How would this dose be altered in the setting of an intracranial haemorrhage and why? 2 marks