A 24-year-old female is brought in by ambulance with fever and altered mental status. Paramedics report a psychiatric history, details unclear.

1. Complete the comparison between neuroleptic malignant syndrome and serotonin syndrome. 6 marks

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2. List three other toxidromes associated with fever and altered mental status. 3 marks

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The patient’s examination findings are consistent with NMS. Core temperature is measured at 40.1Β°C and GCS 10.

3. Detail three different methods of active cooling you would commence in the ED. 3 marks

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