You are reading an article about a new anticoagulant for the management of atrial fibrillation.

1. Complete the table regarding the interpretation of measurements of central tendency. 6 marks

2. Provide a definition for odds ratio. 1 mark

3. Provide a definition for relative risk. 1 mark

The results of the study describe a 10% relative risk reduction of stroke per year for the new drug in comparison with warfarin. The study reports a stroke risk of 5% per year for patients on warfarin.

4. In a population of 1000 patients with atrial fibrillation, provide the number of patients expected to suffer a stroke on each medication. 2 marks

5. What is the absolute risk reduction of stroke in this cohort on the new drug? 1 mark

6. What is the number needed to treat to prevent one stroke by using the new drug instead of warfarin? 1 mark