A 55-year-old man presents with acute atraumatic ankle pain and a low-grade fever.

Hot swollen ankle

1. State three clinical features demonstrated in the photograph. 3 marks

2. List five differential diagnoses for his presentation and a definitive investigation finding for each. 5 marks

A joint aspirate is performed: Appearance Cloudy yellow WCC 40,000 /uL %PMNs 70% Gram stain Negative Crystals negatively birefringent

3. State the diagnosis based on joint aspirate results. 1 mark

4. List three medications with doses that could be used to manage this problem and provide a relative contraindication for each. 3 marks