SAQ Stack

Short Answer Questions for ED Fellowship Study

Case: Checkpoint inhibitor colitis

A 63-year-old male comes into your ED. Hey! You’ve met him before; metastatic melanoma, brain mets, pretty much coning then, but recovered and discharged home on nivolumab and ipilimumab. TODAY, he’s come in with lower abdominal pain, bloody diarrhoea and low-grade temp. His inflammatory markers are moderately elevated.

Checkpoint inhibitor colitis

1. What is the diagnosis, and the (2) most likely causes? (3 marks) 3 marks

★ ★ ★ ★ ★

These CPI (check-point inhibitor) drugs are quite different to OG (original gangster) chemo.

2. How do their mechanisms differ? What kind of adverse effects, or general consequences do you most commonly see in ED as a result?(4 marks) 4 marks

★ ★ ★ ★ ★

3. List (6) adverse effects of CPIs from (6) different organ systems. (6 marks) 6 marks

★ ★ ★ ★ ★

4. What are the (5) most important prongs of his management, with dosing as appropriate? (5 marks) 5 marks

★ ★ ★ ★ ★
SAQ Home

This case forms part of a collaborative marking project designed to support fellowship preparation. In the week leading up to each tutorial, you can contribute answers to any active case. If you contribute, your answers may be reviewed, marked, and used to refine the model answers during the weekly fellowship teaching sessions.

All responses are displayed anonymously or using anonymised avatars. You remain in full control of your answers and may withdraw them at any time.

Your personal results and updated model answers become available the day after the tutorial.

After the tutorial you can still do the case and self-mark your answers, but your answers will not be included in the group review.