A 65-year-old man presents with ataxia, confusion and headaches.

Ataxia, confusion and headaches

An axial image from his non-contrast CTB is shown.

1. List (4) relevant findings and provide an interpretation. 5 marks

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The patient is on apixaban for atrial fibrillation.

2. What is the mechanism by which apixaban has its therapeutic effect? 1 mark

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3. Outline (2) agents you would consider giving the patient in this situation with a dosage regimen. Note, Andexanet alpha is not available. 4 marks

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The patient’s GCS drops suddenly and you are concerned for uncal herniation.

4. Outline (2) physical signs you would seek to confirm this clinically. 2 marks

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